A Review Of pentobarbital sodium use

A Review Of pentobarbital sodium use

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pentobarbital will reduce the level or effect of alprazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lower the extent or effect of sunitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will minimize the level or effect of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the level or effect of prednisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital improves toxicity of buprenorphine, prolonged-acting injection by pharmacodynamic synergism. Modify Therapy/Keep an eye on Carefully. Coadministration of buprenorphine and benzodiazepines or other CNS depressants will increase possibility of adverse reactions which include overdose, respiratory melancholy, and Loss of life. Cessation of benzodiazepines or other CNS depressants is desired generally.

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Keep track of Intently (1)pentobarbital will lessen the extent or effect of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Warning when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone could enhance and can result in perhaps deadly respiratory depressionSerious - Use Alternative (1)hydrocodone, pentobarbital.

pentobarbital will lessen the level or effect of methylprednisolone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will reduce the level or effect of nilotinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will lower the level or effect of donepezil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.

pentobarbital will lessen the level or effect of venetoclax by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Keep track of Carefully (one)pentobarbital will lower the extent or effect of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead into a minimize in fentanyl plasma concentrations, insufficient efficacy get more info or, quite possibly, advancement of a withdrawal syndrome inside of a client who has formulated Actual physical dependence to fentanyl. Soon after halting a CYP3A4 inducer, as the effects on the inducer drop, the fentanyl plasma concentration will increase which could improve or extend both equally the therapeutic and adverse effects.

pentobarbital will reduce the extent or effect of dexamethasone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will reduce the level or effect of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.